System biology provides the basis to understand the behavioral properties of complex biological organisms at different levels of abstraction.Traditionally, analysing systems biology based models of various diseases have been carried out by paper-and-pencil based proofs and simulations.However, these methods cannot provide an accurate Meat Grinder P
A surface with large reflection variations represents one of the biggest challenges for optical 3D shape measurement.In this work, we propose an alternative hybrid 3D shape measurement approach, which combines the high accuracy of fringe projection profilometry (FPP) with the robustness of laser stripe scanning (LSS).To integrate these two technolo
Type 1 diabetes mellitus (T1D) is due to autoimmune destruction of pancreatic beta-cells.Previously, we have shown that intravenously administered bone marrow-derived multipotent mesenchymal stromal cells (MSCs) allows pancreatic islet recovery, improves insulin secretion and reverts hyperglycemia Sealant in low doses streptozotocin (STZ)-induced d
Abstract Background Familial hypercholesterolemia (FH) is an inherited disorder with markedly elevated low-density lipoprotein cholesterol (LDL-C) and premature atherosclerotic cardiovascular disease.Although many mutations have been reported in FH, only a few have been identified as pathogenic mutations.This study aimed to confirm the pathogenicit